Not all proteins arise from consecutive codons. We developed a new tool - PRFect - to identify programmed ribosomal frameshifts.
Designed, built, trained, and tested with #phage genomes, it also works on #bacteria and #eukaryotes too.
https://www.biorxiv.org/content/10.1101/2023.04.10.536325v1
Designed, built, trained, and tested with #phage genomes, it also works on #bacteria and #eukaryotes too.
https://www.biorxiv.org/content/10.1101/2023.04.10.536325v1
Programmed ribosomal frameshifts, and how to find them
One of the stranger phenomena that can occur during gene translation is where, as a ribosome reads along the mRNA, various cellular and molecular properties contribute to stalling the ribosome on a slippery sequence, shifting the ribosome into one of…bioRxiv