It's been a big mystery why giant viruses encode so many proteins involved in vesicular transport and cytoskeletal dynamics. This interesting paper examined a dynamin homolog and found evidence that it's involved in mitochondrial membrane remodelling during infection.
A Novel Group of Dynamin-Related Proteins Shared by Eukaryotes and Giant Viruses Is Able to Remodel Mitochondria From Within the Matrix
https://academic.oup.com/mbe/article/40/6/msad134/7190697?login=false
#viruses #GiantViruses #virology
A Novel Group of Dynamin-Related Proteins Shared by Eukaryotes and Giant Viruses Is Able to Remodel Mitochondria From Within the Matrix
Abstract. The diverse GTPases of the dynamin superfamily play various roles in the cell, as exemplified by the dynamin-related proteins (DRPs) Mgm1 and Opa1, whSheikh, Shaghayegh (Oxford University Press)