Major paper! The team found that fibrinogen (which converts to fibrin):
-binds to spike
-forms clots + neuro issues
-acute stage fibrinogen = predictive biomarker of #LongCovid cog dysfunction!
-suppresses natural killer (NK) cells (which clear virus!)
https://www.nature.com/articles/s41586-024-07873-4 1/
Fibrin drives thromboinflammation and neuropathology in COVID-19 - Nature
Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.Nature