To all #mitochondria enthusiasts out there: we just released mitoMouse, a metabolic model for mouse mitochondria. It is based on the well-known and detailed human MitoCore model, which we updated with latest knowledge on the CoQ crossroad; and translated to SBML3 and Jupyter for easy usage. mitoMouse has 390 genes and 445 metabolites involved in 560 unique reactions. Find here our preprint with all details: https://www.biorxiv.org/content/10.1101/2023.01.02.522468v1
Feedback and collaborations are welcome!
Feedback and collaborations are welcome!
MitoMouse is a model reconstruction of murine mitochondrial metabolism
Mitochondria, apart from being the powerhouses of our cells, are key players in cellular metabolism and homeostasis.bioRxiv