Highlight: Unlocking the Ancient Origins of Cell Death
https://doi.org/10.1093/gbe/evad172
"They propose that early protoeukaryotes were predators, relying on bacterial prey. These bacteria, in response to predation, produced toxins as a defense mechanism. Over time, these bacteria were domesticated to serve as mitochondria within eukaryotic cells, and their toxins evolved into apoptotic factors. "