A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias https://doi.org/10.1371/journal.pbio.3002007 #microbiology #bioinformatics
A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias
A large-scale examination of differential RNA expression study datasets submitted to the NCBI GEO repository from 2008-2020 reveals widespread bias, as assessed by the distribution of p values and estimated proportions of true null hypotheses.doi.org