#AcademicPublishing #Virology
Reviewed pre-print at @eLIFE now online which describes our screen for host mechanisms that limit the ability to activate HIV from latency and identifies a target that could be druggable: "Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal" https://doi.org/10.7554/eLife.103064.1 Revisions for the paper should not be too difficult. Also good timing for the first author, Carley Gray, whose defense is tomorrow afternoon.
Reviewed pre-print at @eLIFE now online which describes our screen for host mechanisms that limit the ability to activate HIV from latency and identifies a target that could be druggable: "Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal" https://doi.org/10.7554/eLife.103064.1 Revisions for the paper should not be too difficult. Also good timing for the first author, Carley Gray, whose defense is tomorrow afternoon.
Frank Aylward
in reply to Michael Emerman • • •I was just discussing HIV with a colleague today. During an HIV infection is most of the virus in the integrated/latent state?
Michael Emerman
in reply to Frank Aylward • • •