Tick Borne Encephalitis Virus (TBEV) is found in northern latitudes from England to Siberia, with variants across North America.
Daniel Růžek's lab has been doing some great work studying this possibly common, but under-diagnosed, pathogen.
Their latest paper describes how they used a Leishmania expression system to produce TBEV virus-like particles (VLP).
When used as a vaccine, the VLPs provided full protection from lethal TBEV in mice.
https://doi.org/10.1016/j.antiviral.2022.105511
#virus #virology @virology
Daniel Růžek's lab has been doing some great work studying this possibly common, but under-diagnosed, pathogen.
Their latest paper describes how they used a Leishmania expression system to produce TBEV virus-like particles (VLP).
When used as a vaccine, the VLPs provided full protection from lethal TBEV in mice.
https://doi.org/10.1016/j.antiviral.2022.105511
#virus #virology @virology