Another crucial study from Shira Weingarten-Gabbay et al. characterizing fundamentals of #SARSCoV2 immunity:
▫️ Any protein expressed is an ‘antigenic liability’ for the virus
▫️ MHC class I and II ‘see’ different antigen repertoires
▫️ Spike is just one of many important viral proteins
1/3
https://www.biorxiv.org/content/10.1101/2023.05.26.542482v1
▫️ Any protein expressed is an ‘antigenic liability’ for the virus
▫️ MHC class I and II ‘see’ different antigen repertoires
▫️ Spike is just one of many important viral proteins
1/3
https://www.biorxiv.org/content/10.1101/2023.05.26.542482v1
The HLA-II immunopeptidome of SARS-CoV-2
Targeted synthetic vaccines have the potential to transform our response to viral outbreaks; yet the design of these vaccines requires a comprehensive knowledge of viral immunogens, including T-cell epitopes.bioRxiv