Into the #Unknome. The function of many human genes still remains mysterious; @mjafreeman, Sean Munro &co present an “Unknome database,” and show that screens focusing on the "Unknome" can shed light on fundamental biological processes #PLOSBiology https://plos.io/3YqumhS
Functional unknomics: Systematic screening of conserved genes of unknown function
The human genome contains many genes whose function remains mysterious, despite decades of research; this study presents a publicly available “Unknome database” and reveals that genetic screens that focus on this "unknome" can help shed light on fund…plos.io