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Anyone have advice on how to get the Spades genome assembler to use less memory?

#Spades #bioinformatics

https://github.com/ablab/spades

in reply to Ben Fulton

what size genome are you trying to assemble? What kind of memory constraint do you have?
in reply to Ben Fulton

for some data I switch to megahit when spades keeps crashing. Spades has huge ram requirements and I've never had luck trying to reduce it.

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