If you work at an r1 in the US, it's likely that at least some of them will bankrupt in the next year. New guidance issued instantly capping indirects at 15%.
Those that don't go bankrupt are going to be purged of a substantial amount of staff and faculty.
grants.nih.gov/grants/guide/no…
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. ODgrants.nih.gov