IL-6 is such a fascinating cytokine.
Here it is modulating different dendritic cell subsets
@JExpMed
#immunology #DC #cytokine #science
https://rupress.org/jem/article/220/10/e20221757/214227/IL-6-selectively-suppresses-cDC1-specification-via?guestAccessKey=48cccc06-d788-423c-889f-51498d95a918&utm_source=NewJournalContent%27&%27utm_campaign%27=%27JEM%27&%27utm_medium%27=%27Email&nbd=28080031447&nbd_source=campaigner&_ccCt=g843-2ph4e3-co3ru7-cwe4ixj2
IL-6 selectively suppresses cDC1 specification via C/EBPβ
We show that tumor-derived IL-6 blocks the development of type 1 classical dendritic cells through the induction of C/EBPβ in the common dendritic cell progenitKim, Sunkyung (Rockefeller University Press)