'To address this critical knowledge gap, we conducted a comprehensive cross-species analysis of transcriptomic data from over 6000 blood samples from macaques and humans infected with one of 31 viruses, including #Lassa, #Ebola, #Marburg, #Zika, and #dengue.'
#Immunology #Virology #preprint

biorxiv.org/content/10.1101/20…

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

Viral pandemics and epidemics pose a significant global threat, with emerging and re-emerging viruses responsible for four pandemics in the 21st century alone.

^bioRxiv

We mapped the global climate-driven transmission potential of #dengue by Aedes #aegypti (1981-2019) & offer a database & R-package as resources towards the identification of past and recent transmission hotspots.

This was hard work by Taishi Nakase, a student from the MSc programme Modelling for Global Health, from NDMOxford@twitter UniofOxford@twitter. Thanks also to the support of Mittenavoig@twitter & UriObolski@twitter climade_health@twitter

nature.com/articles/s41597-023…

A Phylogenetic Study of Dengue Virus in Urban Vietnam shows Long-term Persistence of Endemic Strains

"We observed 5 viral lineages co-circulating in Nha Trang from three DENV serotypes, with two likely to have remained as uninterrupted transmission chains for a decade. This, suggests clade cryptic persistence in the area, even in during periods of low reported incidence."

academic.oup.com/ve/advance-ar…

#virology #viruses #dengue #flaviviruses

A Phylogenetic Study of Dengue Virus in Urban Vietnam shows Long-term Persistence of Endemic Strains

AbstractBackground. DENV causes repeated outbreaks of disease in endemic areas, with patterns of local transmission strongly influenced by seasonality, importat

^{Ashall, James (Oxford University Press)}