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Items tagged with: Crystallography

"In my view, all that is necessary for faith is the belief that by doing our best we shall succeed in our aims: the improvement of mankind."

Happy birthday Rosalind Franklin!

Her work was central to the understanding of the molecular structure of DNA. Though she was recognized for her other work in her time, her work on DNA was not appreciated until after her death.

https://en.wikipedia.org/wiki/Rosalind_Franklin

The Rosalind Franklin question.
https://physicsworld.com/a/the-rosalind-franklin-question/?utm_campaign=PW-FB-PHL-072424&utm_medium=social&utm_source=facebook

#science #crystallography #womeninscience

Rosalind Franklin with microscope in 1955. MRC Laboratory of Molecular Biology The photograph is from 1955, during the peak of Franklin’s research career. This period was marked by significant advancements in molecular biology and the study of DNA. Rosalind Franklin, the pioneering scientist known for her crucial contributions to the discovery of the DNA double helix structure, is depicted in this photograph. She is seen sitting or standing at a laboratory bench, intently working with a microscope.
X-ray diffraction image of the double helix structure of the DNA molecule, taken 1952 by Raymond Gosling, commonly referred to as "Photo 51", during his work with Rosalind Franklin on the structure of DNA. Photograph 51 is an X-ray diffraction image of DNA, famously taken by Rosalind Franklin. The image reveals a series of dark, X-shaped patterns made by X-ray beams scattering off a crystallized sample of DNA. The photograph displays a distinct cross pattern in the center, surrounded by concentric rings. This pattern indicates the helical structure of DNA. The X-shaped diffraction pattern is characteristic of a helical structure, specifically suggesting the presence of a double helix. The image is marked by varying shades of black and gray, highlighting the intensity of the diffracted X-rays at different angles. The clear definition of the cross pattern is crucial, as it provides insight into the periodicity and symmetry of the DNA structure.

The Rosalind Franklin question – Physics World

Why are we still fascinated by the Dark Lady of DNA?
Robert P Crease (Physics World)
#science #womeninscience #crystallography

Alphafold 3 server has dropped, kids. https://golgi.sandbox.google.com/about

Can do select small mols, PTMs, Nucleic acids and ions.

#StructuralBiology @strucbio #Science #Research #Crystallography #CryoEM #NMR

AlphaFold Server

golgi.sandbox.google.com
#science #Research #cryoem #structuralbiology #crystallography #NMR @StrucBio group

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