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Items tagged with: epidemiology

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1/2
Hmm...

A recent paper looked at evolution of #SARSCoV2 *within* different tissues, which might raise a few questions.

Specifically, the authors found evidence that the #virus might evolve independently in different tissues, especially in immune-privileged sites.

But that's not all...

"High-depth sequencing characterization of viral dynamics across tissues in fatal COVID-19 reveals compartmentalized infection"
nature.com/articles/s41467-022…
#virology #epidemiology #InfectiousDisease

High-depth sequencing characterization of viral dynamics across tissues in fatal COVID-19 reveals compartmentalized infection - Nature Communications

Here, by high-resolution SARS-CoV-2 sequencing, genomic and transcriptomic analyses from tissue samples, Normandin et al.
Nature
#Virus #epidemiology #virology #infectiousdisease #sarscov2

1/6
🦠 A Few More #Mpox ( #MonkeyPox) Pandemic Updates 🦠

"Assuming APOBEC-editing is characteristic of [mpox] infection in human hosts, we propose an APOBEC clock that – at a rate of ~6 APOBEC3 mutations per year – estimates [mpox] has been circulating in humans since 2016."
biorxiv.org/content/10.1101/20…

#virus #virology @virology #epidemiology #InfectiousDisease

Putative APOBEC3 deaminase editing in MPXV as evidence for sustained human transmission since at least 2016

Mpox is often described as being endemic in West and Central Africa as a zoonotic disease that transmits through contact with the reservoir rodent host, likely a species of African squirrel.
bioRxiv
#Virus #monkeypox #epidemiology #virology #infectiousdisease #mpox @u/virology

7/6
Interesting report on #Mpox #virus:
(AKA #MonkeyPox or #MPXV)

"We monitored SARS-CoV-2 & MPXV genomes in the air... in Madrid nightclubs... in 2022.
...
MPXV in the air had increased considerably on Aug 8, with 57% of positive samples containing more than 100 genomes per [cubic meter]; this date coincided with the peak incidence of mpox in Spain."

The authors suggest that air sampling might be a useful surveillance method.

#virology #epidemiology #InfectiousDisease
doi.org/10.1016/S2666-5247(23)…

Redirecting

doi.org
#Virus #monkeypox #epidemiology #virology #infectiousdisease #mpox #MPXV

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Have you ever had a weak positive test for West Nile #virus only to test negative on a subsequent test?

One recurring problem with #epidemiology of #flavivirus #InfectiousDisease is that antibody tests for one flavivirus happen to be highly crossreactive with other flaviviruses.

That is a problem addressed in:

"Co-Circulation of West Nile, Usutu, and Tick-Borne Encephalitis Viruses in the Same Area: A Great Challenge for Diagnostic and Blood and Organ Safety"
mdpi.com/1999-4915/15/2/366
@virology

Co-Circulation of West Nile, Usutu, and Tick-Borne Encephalitis Viruses in the Same Area: A Great Challenge for Diagnostic and Blood and Organ Safety

Viral infections caused by viruses from the family Flaviviridae such as Zika (ZIKV), Dengue (DENV), yellow fever (YFV), tick-borne encephalitis (TBEV), West Nile (WNV), and Usutu (USUV) are some of the most challenging diseases for recognition in cli…
MDPI
#Virus #epidemiology #infectiousdisease #Flavivirus @u/virology

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