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Items tagged with: HGT
Ever wondered why your #TRIS-buffered solutions turn turbid on the shelf so quickly? Look no further, it’s #pseudomonas. new study from our lab out as a preprint describing a complete TRIS degradation pathway in #bacteria https://www.biorxiv.org/content/10.1101/2023.08.01.551466v1.abstract?%3Fcollection= #microbiology #HGT #biorxiv
A patchwork pathway of apparently recent origin enables degradation of the synthetic buffer compound TRIS in bacteria
The widely used synthetic chemical 2-amino-2-hydroxymethyl-propane-1,3-diol (TRIS) was long considered to be biologically inert. Herein, we describe a complete degradation pathway for the catabolism of TRIS in bacteria.bioRxiv
This is super cool... and a great example of Horizontal Gene Transfer #HGT https://www.pnas.org/doi/10.1073/pnas.2305871120
Empirical Evidence That Complexity Limits Horizontal Gene Transfer
https://academic.oup.com/gbe/article/15/6/evad089/7180211?login=false
Empirical Evidence That Complexity Limits Horizontal Gene Transfer
Abstract. Horizontal gene transfer (HGT) is a major contributor to bacterial genome evolution, generating phenotypic diversity, driving the expansion of proteinBurch, Christina L (Oxford University Press)