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In our monthly Classic Papers in HIV journal club, Episode 19, https://research.fredhutch.org/emerman/en/courses/classic-papers-in-hiv-biology-journal-club.html we discussed papers establishing that lentiviruses (the type of virus that includes HIV) have infected at least some primates for millions of years through the finding of copies of an ancient lentiviral infection in the genomes of Malagasy Lemurs. https://doi.org/10.1073/pnas.0807873105 and https://doi.org/10.1371/journal.pgen.1000425 #Virology #HIV #ClassicPaperJournalClub #Science 1/7
Parallel Germline Infiltration of a Lentivirus in Two Malagasy Lemurs
Author Summary Retroviruses are RNA viruses that are reverse transcribed into DNA and inserted into the host's genome. Though this process happens most frequently in somatic cells (e.g.doi.org