What do #nanopore #sequencing #bioinformatics folks think about this one? New preprint on hashing raw nanopore signals and using them directly for de-novo assembly.

arxiv.org/abs/2503.02997v1

Hypothetical blow5-to-assembly pipe would be interesting, though figuring it out is way out of my depth.

Enabling Fast, Accurate, and Efficient Real-Time Genome Analysis via New Algorithms and Techniques

The advent of high-throughput sequencing technologies has revolutionized genome analysis by enabling the rapid and cost-effective sequencing of large genomes.

^arXiv.org

troubleshooting a PromethION run - got low pore occupancy and I suspect we overloaded it. Aimed for 10 fmol but possibly added more.

Any tips for confirming or other ideas?

#nanopore @nanopore