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I just found my read of the day:
https://www.biorxiv.org/content/10.1101/2022.12.31.521782v2
It makes so much sense to me that differentiation pathways in T cells(and biological processes i general) are much more flexible than currently depicted in literature! Why would a cell be fully stuck in one state with no way to return? HIgh time for studies like this to correct our current view on #immunology #memory #T cell #differentiation #gene regulation. So i look forward to read it!
https://www.biorxiv.org/content/10.1101/2022.12.31.521782v2
It makes so much sense to me that differentiation pathways in T cells(and biological processes i general) are much more flexible than currently depicted in literature! Why would a cell be fully stuck in one state with no way to return? HIgh time for studies like this to correct our current view on #immunology #memory #T cell #differentiation #gene regulation. So i look forward to read it!
Flexible and scalable control of T cell memory by a reversible epigenetic switch
The immune system encodes information about the severity of a pathogenic threat in the quantity and type of memory cell populations formed in response.bioRxiv