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Items tagged with: transposons
Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk
https://www.nature.com/articles/s41588-023-01390-2
Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk - Nature Genetics
MEGAnE is a new tool to detect and genotype mobile element variants (MEVs) from short-read whole-genome sequencing datasets. Genetic analyses implicate MEVs as population-specific drivers of gene expression variation and disease risk.Nature
https://www.nature.com/articles/s41396-023-01414-z
#phages #viruses #transposons
Unexplored diversity and ecological functions of transposable phages - The ISME Journal
The ISME Journal - Unexplored diversity and ecological functions of transposable phagesNature
Phylogenomics of the Maverick Virus-Like Mobile Genetic Elements of Vertebrates
Nicely underscores the emerging importance of large DNA transposons/EVEs in eukaryotic evolution
"We conclude that vertebrate Mavericks form an ancient lineage of aquatic dsDNA viruses which are probably still functional in some vertebrate lineages."
https://academic.oup.com/mbe/article/38/5/1731/6108104
#transposons #genetics #evolution
Phylogenomics of the Maverick Virus-Like Mobile Genetic Elements of Vertebrates
Abstract. Mavericks are virus-like mobile genetic elements found in the genomes of eukaryotes. Although Mavericks encode capsid morphogenesis homologs, their viBarreat, Jose Gabriel Nino (Oxford University Press)
Giant Transposons in Eukaryotes: Is Bigger Better?
https://academic.oup.com/gbe/article/11/3/906/5364020
"...the size limitations previously placed on mobilizable DNA units in eukaryotes may have been due in part to our inability to assemble large contiguous stretches of repetitive DNA in complex genomes."
#genetics #genomics
Giant Transposons in Eukaryotes: Is Bigger Better?
Abstract. Transposable elements (TEs) are ubiquitous in both prokaryotes and eukaryotes, and the dynamic character of their interaction with host genomes bringsArkhipova, Irina R (Oxford University Press)
Ten things you should know about transposable elements
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1577-z
#genomics #transposons #evolution #genetics
Ten things you should know about transposable elements - Genome Biology
Transposable elements (TEs) are major components of eukaryotic genomes. However, the extent of their impact on genome evolution, function, and disease remain a matter of intense interrogation.BioMed Central