IL-6 is such a fascinating cytokine.
Here it is modulating different dendritic cell subsets
@JExpMed
#immunology #DC #cytokine #science
rupress.org/jem/article/220/10…
We show that tumor-derived IL-6 blocks the development of type 1 classical dendritic cells through the induction of C/EBPβ in the common dendritic cell progenitKim, Sunkyung (Rockefeller University Press)
The 'There Are Such Things As Cooties' book doesn't appear to be available in UK.
I have a serious need to know as osculation, for me, has always carried great risk, #autoimmunesystem highly compromised.
The first few months of a new romantic relationship is fraught with a horrid cascade of immune response symptoms. And yet, I still do it!!! It's a really difficult one to resist.
#science #biology #immunology #immunesystem
My first post on Mastodon after a whole lot of lurking and boosting, so I'm treating this as a mini #introduction for myself
I'm an #immunology PhD candidate at #ColumbiaUniversity medical center, and we just published a study of #TissueSpecifity of human #Tcell identity and clonal expansion in barrier sites, using #CyTOF, #scRNAseq, and #TCR #sequencing!
nature.com/articles/s41590-022…
Farber and colleagues examine the phenotypic, transcriptomic, clonal, and functional differences between tissue-resident T cells in various barrier tissue sites relative to T cells in lymphoid organs and circulation in humans.Nature
'To address this critical knowledge gap, we conducted a comprehensive cross-species analysis of transcriptomic data from over 6000 blood samples from macaques and humans infected with one of 31 viruses, including #Lassa, #Ebola, #Marburg, #Zika, and #dengue.'
#Immunology #Virology #preprint
biorxiv.org/content/10.1101/20…
Viral pandemics and epidemics pose a significant global threat, with emerging and re-emerging viruses responsible for four pandemics in the 21st century alone.bioRxiv
Bioinformatician with PhD and experience in immunology and single-cell
Institut Curie
Looking for a #bioinformatician with a PhD, experience in #immunology and #single-cell. Come join us at #InstitutCurie in #Paris
See the full job description on jobRxiv: jobrxiv.org/job/institut-curie…...
jobrxiv.org/job/institut-curie…
The international job board for scientists, by scientists. Find science jobs in academia or industry: MSc, PhD, Postdoc, Scientist, Faculty and more!Paul (jobRxiv)
Open position in a great department!
Immunology Lecturer in the Department of Microbiology at the University of Tennessee-Knoxville
An antibacterial peptide encoded in the mitochondrial genome (#preprint).
#immunology #InnateImmunity
"We demonstrate that MOTS-c (mitochondrial open reading frame from the twelve S rRNA type-c) is a mitochondrial-encoded amphipathic and cationic peptide with direct antibacterial and immunomodulatory functions, consistent with the peptide chemistry and functions of known HDPs."
biorxiv.org/content/10.1101/20…
The mitochondrial DNA (mtDNA) can trigger immune responses and directly entrap pathogens, but it is not known to encode for active immune factors. The immune system is traditionally thought to be exclusively nuclear-encoded.bioRxiv
"An analysis of about 450,000 electronic health records has found a link between infections from influenza and other common viruses and an elevated risk of having a neurodegenerative condition such as Alzheimer’s or Parkinson’s disease later in life."
#Virology #AlzheimersDisease #NeuroDegeneration #Neuroscience #Immunology
nature.com/articles/d41586-023…
Study ties common viruses such as flu to Alzheimer’s and other conditions — but the analysis has limitations, researchers warn.Kozlov, Max
I just found my read of the day:
biorxiv.org/content/10.1101/20…
It makes so much sense to me that differentiation pathways in T cells(and biological processes i general) are much more flexible than currently depicted in literature! Why would a cell be fully stuck in one state with no way to return? HIgh time for studies like this to correct our current view on #immunology #memory #T cell #differentiation #gene regulation. So i look forward to read it!
The immune system encodes information about the severity of a pathogenic threat in the quantity and type of memory cell populations formed in response.bioRxiv
