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@ajlewis2

And dont forget about Kizzmekia Corbett the #Immunologist who was on the #moderna team that only took like 2 months to make the formula

#covid #covidvaccine #mRNA

Kizzmekia "Kizzy" Shanta Corbett (born January 26, 1986)

https://en.m.wikipedia.org/wiki/Kizzmekia_Corbett

American immunologist (1986-)

Contributors to Wikimedia projects (Wikimedia Foundation, Inc.)
#covid #mrna #Immunologist #moderna #covidvaccine @Anita Lewis

The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective #mRNA #vaccines against COVID-19.

Despite all the known issues with these (& other) prizes, this one makes me particularly happy: it is extremely well deserved and (another) clear example of what basic science can do for humanity.

#vaccines #nobelprize #mrna

We have a new preprint online! A great collab with the Tresch lab in Cologne. We found that mRNA 🧬 export out of the nucleus is surprisingly slow and and a rate limiting step for mRNA metabolism. Take a look: https://www.biorxiv.org/content/10.1101/2023.05.04.539375v1
#ScienceMastodon #RNA #mRNA #preprint #mpinat

Nuclear export is a limiting factor in eukaryotic mRNA metabolism

The eukaryotic mRNA life cycle includes transcription, nuclear mRNA export and degradation. To quantify all these processes simultaneously, we perform thiol-linked alkylation after metabolic labeling of RNA with 4-thiouridine (4sU), followed by seque…
bioRxiv
#ScienceMastodon #preprint #RNA #mrna #MPINAT

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