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Hello #ScienceMastodon Twitter refugees
#introduction I am a 🇫🇷 molecular & structural biologist working at the CNRS. I study the molecular mechanisms that control human gene expression focusing on #transcription factors & the Pol II machinery
Expect to see here a lot of info on #generegulation, #enhancers, #histone modifications & structural insights into the eukaryotic Transcription Initiation machinery. #CryoEM
I will also highlight #womeninscience to give them the visibility they deserve
Happy Monday again, #ScienceMastodon! The first Research Highlight from JCS Issue 16 features a paper from Toshiyuki Oda and colleagues at the Universities of Yamanashi and Tokyo, using the unicellular algae Chlamydomonas reinhardtii to break down roles of tubulin modifications in ciliary/flagellar motility. #CellBiology #microtubules #flagellates
Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
https://journals.biologists.com/jcs/article/136/16/e136_e1601/325932/Roles-of-ciliary-tubulin-PTMs-in-Chlamydomonas
Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
The cytoskeletal core of cilia and flagella, called the axoneme, is composed of microtubules (MTs), the dynamics of which can be dramatically influenced by post-translational modifications (PTMs) to tubulin C-terminal tails.The Company of Biologists
“Thousands of scientists are cutting back on Twitter, seeding angst & uncertainty.”
That survey with only a 5% response rate went viral & got me wondering about other evidence & how the #ScienceTwitter #MastodonMigration was panning out.
So I updated my study tracker & wrote a new post @PLOS : https://absolutelymaybe.plos.org/2023/08/20/how-is-science-twitters-mastodon-migration-panning-out/
tl;dr There's been a big recent surge here; the future of #ScienceMastodon looks bright; ScienceX is materially diminished tho the network is still there.
How Is Science Twitter's "Mastodon Migration" Panning Out? - Absolutely Maybe
“Thousands of scientists are cutting back on Twitter, seeding angst and uncertainty.” And Mastodon was the most common destination if they opened…Hilda Bastian (Absolutely Maybe)
#ScienceMastodon #RNA #mRNA #preprint #mpinat
Nuclear export is a limiting factor in eukaryotic mRNA metabolism
The eukaryotic mRNA life cycle includes transcription, nuclear mRNA export and degradation. To quantify all these processes simultaneously, we perform thiol-linked alkylation after metabolic labeling of RNA with 4-thiouridine (4sU), followed by seque…bioRxiv
However, I think we need to be mindful of the inclusivity of the spaces we create, maintain, and implicitly support. I recently donated to the upkeep of my server. However, if the @admin team decides not to revisit the rules, then I may look to change server as supporting diversity, equity, inclusion, justice, and belonging are vitally important to me.
#ScienceMastodon
I don't think such people should be unwelcome on https://fediscience.org and believe the current rules are hence overly exclusive.
I really hope that the rules can be changed to be more inclusive and allow this instance to become a diverse and welcoming home for all scientists.
#ScienceMastodon
