The best practice for microbiome analysis using R

Abstract. With the gradual maturity of sequencing technology, many microbiome studies have published, driving the emergence and advance of related analysis tool

Every base everywhere all at once: pangenomics comes of age

Multi-genome assemblies called pangenomes can capture genetic diversity in a species, but researchers are still working out how best to build and explore them.

JASPER: A fast genome polishing tool that improves accuracy of genome assemblies

Advances in long-read sequencing technologies have dramatically improved the contiguity and completeness of genome assemblies.

A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias

A large-scale examination of differential RNA expression study datasets submitted to the NCBI GEO repository from 2008-2020 reveals widespread bias, as assessed by the distribution of p values and estimated proportions of true null hypotheses.

An overview of bioinformatics courses delivered at the academic level in Italy: Reflections and recommendations from BITS

In Italian universities, bioinformatics courses are increasingly being incorporated into different study paths.

Pathogen detection in RNA-seq data with Pathonoia - BMC Bioinformatics

Background Bacterial and viral infections may cause or exacerbate various human diseases and to detect microbes in tissue, one method of choice is RNA sequencing.

Matreex: compact and interactive visualisation of large gene families provides evidence for loss of intraflagellar transport in a myxozoan

Studying gene family evolution strongly benefits from insightful visualisations. However, the ever-growing number of sequenced genomes is leading to increasingly larger gene families, which challenges existing gene tree visualisations.

High-resolution metagenomic reconstruction of the freshwater spring bloom - Microbiome

Background The phytoplankton spring bloom in freshwater habitats is a complex, recurring, and dynamic ecological spectacle that unfolds at multiple biological scales.

Bioinformatician / Postdoc (m/f/d)

The MPI-CBG is looking for a Bioinformatician (m/f/d)

NCBI Minute: Using BLAST Well

Presented October 3, 2018. In this webinar, the NCBI BLAST team lead will show you how to be more effective with NCBI’s standalone BLAST applications. You wi...

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