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The human #OAS1 protein restricts #SARSCoV2 replication, but #HorseshoeBat OAS1 has lost this ability. @spyroslytras @WilsonLabCVR &co resurrect the 60,000,000 yr old ancestral bat OAS1, revealing how this ancient #antiviral mechanism was lost #PLOSBiology plos.io/3N6fWPx


New future for decentralized communication is here. Roundcube 📧 the open-source email pioneer, has found its new home with Nextcloud!

What does it mean for the productivity industry? And what about Nextcloud Mail?

Find out in our blog!

nextcloud.com/blog/open-source…


in reply to Muse

That's been a fear of mine since e-books started rising in popularity.

Suddenly, a title vanishes from Amazon or Apple because someone doesn't like it. We're already going through this with language and physical books, it really won't be long before we get Moms Shilling for Fascism working to ban content from streams.



This ad is from 1975. I always thought they were the Tetley Tea Elves rather than Folk.
Mike Oldfield put out a version of the "Portsmouth", which reminds me of this advert.

youtu.be/N9nbAwrkXlY?si=47rXfo…



Day10: Ten Days, Ten Films.


My last day!!! I hope to see some of you start a list as well!

This is a lot of fun! So long as you don’t make this too hard or too easy!
Over ten days you pick an image from a film without any title to give away where it is from, so that people can guess. You can also nominate others to do the same. That way more people are in on the game! (or not–your choice 😀 )

But remember: NO SPOILERS! If you recognise a film, don’t say what it is! Say something that indicates you know, but allows others to guess as well. Your messages then become helpful hints!

no spoilers

#TenDaysTenFilmsTenFriends or #TenDaysTenFilmsNoFriends



It has been moving to see the emails I have been getting about my recent essay, "The Trouble with 'Gender Ideology.'" Most of my writing has focused on other things, but work on gender always seems to touch readers most deeply. americamagazine.org/faith/2023…


From now on, I am calling my dietary preferences "flight training."


Every now and then, technologists are able to translate their strongly held beliefs into action for the benefit of society. Sometimes these actions result in new features, apps or platforms but it's especially powerful when this happens at the protocol level.

In the latest episode of Dot Social I talk with @evan about how he helped get #ActivityPub started, how it's going, and what he hopes for next. Check it out here.

about.flipboard.com/inside-fli…




How To Learn Rust... Write A GPU Driver?!? #Linux #YouTube youtu.be/-h0q6dG4Rvk
in reply to Brodie Robertson

If you can write a (good) GPU driver in rust you’re probably pretty good at rust so sure I guess
in reply to Brodie Robertson

For learning Rust, here are few projects a beginner can work on to get used to with the borrow checker. I recommend beginners to learn the standard library before diving into third party libraries.

Beginner Projects
- Socket Programming (std::net)
- CLI Program (std::env)
- Simple File program (std::fs)



Minimalist or maximalist? The life of a #microbe a mile underground
phys.org/news/2023-11-minimali… paper: ami-journals.onlinelibrary.wil…

Magdalena Osburn: "The deep subsurface #biosphere is enormous; it's just a vast amount of space... Many of the #microbes we found were either minimalist: ultra-streamlined with one job that it does very well alongside a close consortium of collaborators, or it can do a little bit of everything. These maximalists are ready for every resource that comes along."

This entry was edited (2 years ago)


Great news! If you're in the U.S., my publisher is doing a Goodreads giveaway for THE GRAMMAR DAILY.

Enter now for a chance to win a copy!

goodreads.com/giveaway/show/37…



Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with bacterial hosts

nature.com/articles/s41467-023…

#phages #viruses #evolution #genomics



Finished boneyard sweethearts! This is the perfect festival sweater as I used yarn from many small dyers for the color work. The base yarn is a sturdy and snuggly Romney from Apple Creek Merinos. #knitting #knittersofmastodon


Untitled Goose Game is in @AmongUsGame !! 🚀

Check out their in-game store now to get the Indie Cosmicube and show off our new bean look.

So cool to be part of this with a bunch of other fellow indies. Can't wait to see you represent us as the Impostor. 😈




Event Idea: Go to IKEA and make the shorks (and other animals) more presentable.

Instead of the hajpile you often see in IKEA, put down effort and put them in the upright position.

Risk: A non-zero chance of getting banned from IKEA
Benefit: h a p p i n e s s :blobhaj_hug_tinybla:



There is an open #GitHub issue for the #Nextcloud #Android app, which renders the app useless for anyone affected.

Issue opened on Sep 17, Now 2 1/2 months and 114 comments later this Issue is still open, and no sign that it will be fixed anytime soon.

github.com/nextcloud/android/i…



Robert De Niro tells Gotham Awards his speech was edited without his knowledge


Apple Censored his Speech evidently they don't want to offend their Republican Masters...

This is Outrageous

#News #Apple #GothamAwards #Censorship #DeNiro #BBC #TakeBackTechnology #TakeBackArt #EndRepublicanMeddling




Steam Deck global top seller again thanks to cheaper LCDs and the Steam Deck OLED gamingonlinux.com/2023/11/stea…

#SteamDeck #SteamDeckOLED



An Amazing Wizard is a bland name for a game but it looks like great chaos gamingonlinux.com/2023/11/an-a…

#IndieGame #Linux #SteamDeck



Latest e-newsletter, after a 5-month silence, so there's a good bit to cover. Peripheral: Art, technology, myth and collaboration.

sh1.sendinblue.com/aebpxfms1xp…

This entry was edited (2 years ago)


Recomendamos📚«When Protection Becomes an Excuse For Criminalisation»
Un informe de @APC y @derechosdigital sobre cómo las leyes nacionales contra el cibercrimen se utilizan para silenciar y criminalizar a mujeres y personas LGBTQIA+ en el mundo.

↪️ derechosdigitales.org/wp-conte…



Aether combines Risk of Rain 2 with Wizard of Legend gamingonlinux.com/2023/11/aeth…

#IndieGame #Linux #SteamDeck



I’m traveling for a few weeks and Edith Zimmerman is going to be guest editing the site while I’m away. Welcome, Edith! kottke.org/23/11/please-welcom…
in reply to kottke.org

@jkottke Have a great walk! Give @craigmod a dap for me (we've never met, may never meet, and I'd like to dap him). I expect you to publish an incredibly well designed and copiously photographed book upon your return!


Xorg is dead, long live Wayland - Red Hat Enterprise Linux (RHEL) dropping Xorg gamingonlinux.com/2023/11/xorg…

#Linux #FOSS

in reply to Liam @ GamingOnLinux 🐧🎮

on fedora I still use X11. Kepassxc autotype still doesn't work on Wayland. Hope once x is not available anymore these kind of features are supported.


What Even Is The Point Of NVK #Linux #YouTube youtu.be/gITbp7QhqyA


Post-apocalyptic real-time strategy game Retro Commander is out now gamingonlinux.com/2023/11/post…

#Linux #RTS #IndieGame



GUNHEAD from Alientrap gets Steam Deck improvements gamingonlinux.com/2023/11/gunh…

#SteamDeck #GUNHEAD



Hi all, we have news regarding our plans for RHEL 10, Xorg server and Wayland we want to share with you. We wrote a blog post to that end. With this, we're looking forward to continue building with the community, and gained focus, the future of Linux.

redhat.com/en/blog/rhel-10-pla…



This Thursday from 18:30 CET join us in person or online for the next iteration of the sessions Sometimes Not Available, this time with the Transfeminist Digital Care Network. #varia #TFN #gincanamonstra #feministserver varia.zone/en/sometimes-not-av…
in reply to varia

@varia @ephemeral since you just mentioned you missed the last session, you have a second chance this Thursday


From the archives of RTÉ (Ireland's national broadcaster): This show was recorded in 1962 about the establishment of the signal towers for rural radio and television broadcast.

In it an engineer named John O'Keefe described how they chose the sites for masts in an unusual way. Rather than the usual process using contour maps, they made a 3D model of Ireland and placed lights on hills to see how signal would travel. From about 20 mins in here: rte.ie/archives/2012/1022/3426…

in reply to Fionnáin

A linked question to #mastodaoine : I know this is a long shot, but in the documentary that I linked in the last toot, I'd love to know if anyone knew/knew about the engineer John O'Keefe, pictured here.

This was in 1962, and O'Keefe must be in their 50s at the youngest, so over 100 now. More likely there might be a death notice, a living relative, or someone that worked with them. Would be grateful for any help.

in reply to Fionnáin

This is the beginning stages of a new art project on the five regional transmitters in Ireland.

I'm already hooked on the amazing consequences of the banal publication from the European Broadcasting Conference of 1952 (Stockholm), and how frequencies were allocated to different countries.

The steel imported from Norway, electronics from Britain, and regulations decided in Sweden already spread this so far. A single object like a signal tower can have complex social and material relationships.




This is a painting of the Australian pobblebonk frog. I created the frog by dabbing a bazillion little dots onto the canvas. At this size it’s hard to see every single dot! I have gone dotty!
#myart #nature #frogs #art
@Miguela @Kenny Chaffin @Clarice Boomshakala Bouvier


New Outlook is good, both for yourself and 766 third parties.


Some sort of Illuminati sidequest portal
#nature #photography #snow
This entry was edited (2 years ago)


Photos of the forests of the Dandenong ranges always look like they should include a dinosaur or two! In Australia we genuinely have primeval forests with plants from the Eocene. We are talking about these plants fluorishing tens of millions of years ago!

Dandenong ranges forest
by EpicEarthP**n

in reply to Muse

Well, the first thing that is said about the daplogonosaurous is that it is green. It's sort of like a Preying Mantis, but in dinosaur form, but without the friendly smile that one sees on Mantises. Daplogonosaurous is mostly vegan, although at 6:45pm on the 14th of the second month of each season it tries to find, and eat, a BBQ tri-tip sandwich - it is an animal that abides by a printed schedule. Daplogonosaurous is renowned for its ability to hide - which is probably why no fossil remains have ever been found.
in reply to Muse

@Karl Auerbach What an amazing creature! I may need to start making some BBQ tri-tip sandwiches and see if I can lure one out of our primeval forests!


Data from the Kepler #space telescope suggest there may be as many as 300 million potentially habitable planets in our galaxy alone.

We may never have evidence proving whether intelligent life is somewhere out there, but - as Carl Sagan once wrote, “If it’s just us, seems like an awful waste of space.”

in reply to Sheril Kirshenbaum

I'm waiting for the grand discovery of some —‌ to us until then unknown but obvious in retrospect —‌ form of communication where long diatribes between planetary folk have been happening in real time while we muse in darkness.
in reply to Sheril Kirshenbaum

The chances of there *not* being other planets with intelligent life forms is close to zero.


Brickception: a Breakout-style game for desktop browsers in which a popup window acts as the paddle for the main window…but there’s also a mini Breakout game in the popup. So awesome. brickception.xyz/

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