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Items tagged with: cellbiology

Remembering George Palade, born #OTD in 1912. His use of cell fractionation and electron microscopy led to many discoveries and laid a foundation for modern cell biology. I was fortunate to know him late in his career and early in mine. He exemplified everything academic leadership should be. #cellBiology #ElectronMicroscopy
#otd #CellBiology #electronmicroscopy

Good morning!! Cell biology rocks, isn't it?

#microscopy #exm #cellbiology

Expanded COS7 during division, superesolved microtubules in yellow, compacted DNA in blue
Expanded COS7 during division, superesolved microtubules in gold, compacted DNA in gray
#microscopy #CellBiology #exm

New #ISEPpapers! Evolutionary origins of the lysosome-related organelle sorting machinery reveal ancient homology in post-endosome trafficking pathways: Kiran More et al. pnas.org/doi/10.1073/pnas.2403…

#protists #microbes #CellBiology #eukaryogenesis #biology #organelles

diagram of molecular interaction among organelles in a cell
#biology #protists #CellBiology #microbes #iseppapers #organelles #Eukaryogenesis

Elizabeth Villa's lab delivers big time again with in-cell cryo-electron tomography of the nuclear pore complex:

"The molecular architecture of the nuclear basket" by Singh et al. 2024.
cell.com/cell/fulltext/S0092-8…

#CellBiology #CryoEM #ProteinStructure #StructuralBiology

Summary image showing the process of imaging the proteins of the nuclear pore.
#CellBiology #cryoem #ProteinStructure #structuralbiology

Happy Monday again, #ScienceMastodon! The first Research Highlight from JCS Issue 16 features a paper from Toshiyuki Oda and colleagues at the Universities of Yamanashi and Tokyo, using the unicellular algae Chlamydomonas reinhardtii to break down roles of tubulin modifications in ciliary/flagellar motility. #CellBiology #microtubules #flagellates

Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
journals.biologists.com/jcs/ar…

Transmission electron microscopy images showing cross-sections of axonemal microtubules in Chlamydomonas reinhardtii flagella. Axonemes from mutants in which beta-tubulin cannot be glycylated often lack central microtubules resulting in truncated, paralyzed flagella.

Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii

The cytoskeletal core of cilia and flagella, called the axoneme, is composed of microtubules (MTs), the dynamics of which can be dramatically influenced by post-translational modifications (PTMs) to tubulin C-terminal tails.
The Company of Biologists
#ScienceMastodon #CellBiology #microtubules #flagellates

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