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Items tagged with: viruses
Our latest work on marine giant virus diversity -
Assessing the biogeography of marine giant viruses in four oceanic transects
nature.com/articles/s43705-023…
#viruses #marine #ocean #giantviruses
Assessing the biogeography of marine giant viruses in four oceanic transects - ISME Communications
ISME Communications - Assessing the biogeography of marine giant viruses in four oceanic transectsNature
Cheating leads to the evolution of multipartite viruses
In multipartite viruses, the genome is split into multiple segments, each of which is transmitted via a separate capsid.plos.io
Unexplored diversity and ecological functions of transposable phages
nature.com/articles/s41396-023…
Unexplored diversity and ecological functions of transposable phages - The ISME Journal
The ISME Journal - Unexplored diversity and ecological functions of transposable phagesNature
Important study describing a new phylum of herpesvirus relatives that is abundant in the ocean -
Mirusviruses link herpesviruses to giant viruses
nature.com/articles/s41586-023…
I was honored to be asked to review this paper! Wonderful work.
#virology #viruses #herpesviruses #giantViruses
Mirusviruses link herpesviruses to giant viruses - Nature
A phylogeny-guided genome-resolved metagenomic analysis of DNA viruses in the ocean reveals atypical plankton-infecting relatives of herpesviruses that form a putative new phylum dubbed Mirusviricota.Nature
Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
"The viral inner membrane-integrated anchor protein colocalizes with the endoplasmic reticulum (ER), supporting the hypothesis that the biogenesis of the inner membrane is associated with the ER"
Nice confirmation about where the viral inner membrane comes from.
nature.com/articles/s41467-023…
#viruses #giantViruses #virology
Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly - Nature Communications
High morbidity and mortality in aquatic have been caused by iridovirids worldwide. Here the authors present a near-atomic SGIV capsid structure. Functional assays further reveal the relationships between identified capsid proteins and viral assembly.Nature
In-depth study of tomato and weed viromes reveals undiscovered plant virus diversity in an agroecosystem
microbiomejournal.biomedcentra…
In-depth study of tomato and weed viromes reveals undiscovered plant virus diversity in an agroecosystem - Microbiome
Background In agroecosystems, viruses are well known to influence crop health and some cause phytosanitary and economic problems, but their diversity in non-crop plants and role outside the disease perspective is less known.BioMed Central
Non-structural genes of novel lemur adenoviruses reveal codivergence of virus and host
academic.oup.com/ve/advance-ar…
Non-structural genes of novel lemur adenoviruses reveal codivergence of virus and host
Abstract. Adenoviruses are important human and animal pathogens, and are frequently used as vectors for gene therapy and vaccine delivery. Surprisingly, there aVeith, Talitha (Oxford University Press)
Widespread Distribution and Evolution of Poxviral Entry-Fusion Complex Proteins in Giant Viruses
Because of the headline, people are panicking over this article.
It doesnt mean that the virus “would turn people into zombies”. They meant “the virus has been dormant in permafrost for a long time and it has now been resurrected.”
VirBot: an RNA viral contig detector for metagenomic data
academic.oup.com/bioinformatic…
VirBot: an RNA viral contig detector for metagenomic data
AbstractSummary. Without relying on cultivation, metagenomic sequencing greatly accelerated the novel RNA virus detection. However, it is not trivial to accuratChen, Guowei (Oxford University Press)
Identification and characterization of thousands of bacteriophage satellites across bacteria
academic.oup.com/nar/advance-a…
#phages #viruses #microbiology
Identification and characterization of thousands of bacteriophage satellites across bacteria
Abstract. Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit phages for transfer between bacteria. Satellites can encodde Sousa, Jorge A Moura (Oxford University Press)
Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells
journals.plos.org/plospathogen…
Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells
Author summary The co-occurrence of distinct virus populations within a single host occurs commonly, when an individual acquires a second infection before a prior one has been cleared.journals.plos.org
Pathogen detection in RNA-seq data with Pathonoia
bmcbioinformatics.biomedcentra…
#bioinformatics #pathogens #viruses
Pathogen detection in RNA-seq data with Pathonoia - BMC Bioinformatics
Background Bacterial and viral infections may cause or exacerbate various human diseases and to detect microbes in tissue, one method of choice is RNA sequencing.BioMed Central
Intriguing manuscript looking into the range of viruses that form a phage nucleus during infection. Amazing bioinformatics and experimental work, and beautiful figures!
Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY
biorxiv.org/content/10.1101/20…
Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY
We recently discovered that some bacteriophages establish a nucleus-like replication compartment (phage nucleus), but the core genes that define nucleus-based phage replication and their phylogenetic distribution were unknown.bioRxiv
Jumbo phage! The phage nucleus that some can form during infection is pretty amazing. This paper has some interesting structural insights.
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
nature.com/articles/s41467-023…
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice - Nature Communications
To protect from host attack, numerous jumbo bacteriophages establish a micron-scale, protein-based structure to enclose their replicating DNA.Nature
Transcriptomics-Driven Characterization of LUZ100, a T7-like Pseudomonas Phage with Temperate Features
"This transcriptomics-driven characterization of LUZ100 supports recent evidence that T7-like phages should not automatically be assumed to have a strictly lytic life cycle."
A Phylogenetic Study of Dengue Virus in Urban Vietnam shows Long-term Persistence of Endemic Strains
"We observed 5 viral lineages co-circulating in Nha Trang from three DENV serotypes, with two likely to have remained as uninterrupted transmission chains for a decade. This, suggests clade cryptic persistence in the area, even in during periods of low reported incidence."
academic.oup.com/ve/advance-ar…
#virology #viruses #dengue #flaviviruses
A Phylogenetic Study of Dengue Virus in Urban Vietnam shows Long-term Persistence of Endemic Strains
AbstractBackground. DENV causes repeated outbreaks of disease in endemic areas, with patterns of local transmission strongly influenced by seasonality, importatAshall, James (Oxford University Press)
Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes
"Collectively, our data support a model where suppression of quorum-regulated virulence factors by Pf4 allows P. aeruginosa to evade detection by innate host immune responses."
journals.plos.org/plospathogen…
#viruses #virology #symbiosis #phage
Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes
Author summary Pseudomonas aeruginosa is an opportunistic bacterial pathogen that infects wounds, lungs, and medical hardware. P. aeruginosa strains are often themselves infected by a filamentous virus (phage) called Pf.journals.plos.org
Viral dew: Phase separation and the formation of viral replication compartments
Giant Virus Infection Signatures Are Modulated by Euphotic Zone Depth Strata and Iron Regimes of the Subantarctic Southern Ocean
Four principles to establish a universal virus taxonomy
Transforming an existing phenotypic classification of viruses into one based on evolutionary relationships that can accommodate the vast number of viruses characterized in metagenomics and environmental studies is an ongoing challenge.plos.io
The APOBEC3B cytidine deaminase is an adenovirus restriction factor
"we show that adenovirus infection leads to a reduction of the quantity and/or enzymatic activity of the APOBEC3B protein depending on the strains. The A12 strain seems less able to resist APOBEC3B than the B3 or C2 strains, a characteristic which could explain the strong depletion of the APOBEC3-targeted motifs in the A12 genome."
journals.plos.org/plospathogen…
The APOBEC3B cytidine deaminase is an adenovirus restriction factor
Author summary The APOBEC3B protein is overexpressed in many human tumors and promotes genetic diversity and resistance to drug and oncolytic viruses.journals.plos.org
Assessing the biogeography of marine giant viruses in four oceanic transects
Viruses of the phylum Nucleocytoviricota are ubiquitous in ocean waters and play important roles in shaping the dynamics of marine ecosystems.bioRxiv
#Virus control
This exciting new research explores the influence of #virus #infection in changing the balance of organic matter degradation between #bacteria and #eukaryotes in #marine #carboncycling during #phytoplankton blooms.
Based on #mesocosm studies, this research demonstrates how #viruses infecting different #microorganisms change community dynamics and the release and potential fate of marine carbon from primary production.
Learn more in this new research in Nature Communications on:
nature.com/articles/s41467-023…
#microbiology #ecology #MicrobialEcology
Viral infection switches the balance between bacterial and eukaryotic recyclers of organic matter during coccolithophore blooms - Nature Communications
Algal blooms are hotspots of marine primary production that play central roles in microbial ecology and global elemental cycling.Nature
Phylodynamics of deer tick virus in North America
academic.oup.com/ve/advance-ar…
Phylodynamics of deer tick virus in North America
Abstract. The burden of ticks and the pathogens they carry is increasing worldwide. Powassan virus (POWV, Flaviviridae: Flavivirus), the only known North AmericMcMinn, Rebekah J (Oxford University Press)
Wonderful essay by @vincentflora and Assaf Vardi on viruses in the ocean
Viral infection in the ocean—A journey across scales
"Aquatic virology tackles some of the most challenging questions in microbial ecology and oceanography, trying to understand how microorganisms that are invisible to the naked eye can influence large-scale processes, such as biogeochemical cycles, or affect entire marine food webs."
journals.plos.org/plosbiology/…
#viruses #virology #ocean #marine
Viral infection in the ocean—A journey across scales
Viruses are the most abundant biological entity in the ocean. This Essay journeys across several orders of magnitude of biological organization, time, and space, to investigate interactions between hosts and viruses in the ocean and their relevance f…journals.plos.org
Isolation and infection cycle of a polinton-like virus virophage in an abundant marine alga
This is an important study that shows how #virophage have evolved multiple times independently in distinct viral groups. Turns out that #viruses infecting other viruses are quite common!
Also gotta love the opening sentence: "Eukaryotic genomes are a hub where viruses and selfish genetic elements convene" - so true.
Amazing work by the @BejaLab lab!
nature.com/articles/s41564-022…
Isolation and infection cycle of a polinton-like virus virophage in an abundant marine alga - Nature Microbiology
Isolation and characterization of a selfish genetic element with a virophage lifestyle that co-infects a bloom-forming polar algae along with a partner virus.Nature
plos.io/3kJcjDY
Viral infection in the ocean—A journey across scales
Viruses are the most abundant biological entity in the ocean. This Essay journeys across several orders of magnitude of biological organization, time, and space, to investigate interactions between hosts and viruses in the ocean and their relevance f…plos.io
Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee
pubmed.ncbi.nlm.nih.gov/366830…
Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee - PubMed
This article summarises the activities of the Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses for the period of March 2021-March 2022.PubMed
Nice press release on an study that came out earlier this year-
"Israeli-led study claims to uncover 100,000 previously unknown viruses"
timesofisrael.com/israeli-led-…
and the original study: cell.com/cell/fulltext/S0092-8…
Congrats again @Neri !
Israeli-led study claims to uncover 100,000 previously unknown viruses
Researchers hope groundbreaking findings into RNA pathogens could help develop new kinds of antimicrobial drugs and protect against agriculturally harmful fungi and parasiteswww.timesofisrael.com
Wonderful Bio about former postdoc in the lab @giant_virus !
"Monir Moniruzzaman Studies the Secrets of Giant Viruses"
the-scientist.com/scientist-to…
#viruses #microbiology #marine
Monir Moniruzzaman Studies the Secrets of Giant Viruses
The University of Miami researcher studies how a mysterious group of supersized viruses infects and influences the evolution of their hosts.James M. Gaines (The Scientist Magazine)