What do #nanopore #sequencing #bioinformatics folks think about this one? New preprint on hashing raw nanopore signals and using them directly for de-novo assembly.
Hypothetical blow5-to-assembly pipe would be interesting, though figuring it out is way out of my depth.
Enabling Fast, Accurate, and Efficient Real-Time Genome Analysis via New Algorithms and Techniques
The advent of high-throughput sequencing technologies has revolutionized genome analysis by enabling the rapid and cost-effective sequencing of large genomes.arXiv.org
Anyone know anyone who works at @internetarchive ? I'm trying to see if I can get into this screening, but the RSVP I'd "sold out."
Can I just show up?
mailchi.mp/archive.org/email-2โฆ
Join Us for a Screening of Staff Picks from the Prelinger Archives [IN-PERSON]
On Monday, March 24, you're invited to a free showcase of the rare finds and staff insights from a three year mass-digitization project.mailchi.mp
I only need to know 2 things about the Wisconsin Supreme Court election:
1) Judges are the last reasonable roadblock slowing down the Project 2025 plan.
2) Elon Musk and the Project 2025 crew don't want Susan Crawford to win. They're scared.
Susan Crawford. That's the only name I need to know.
The other person's name doesn't matter. Their platform doesn't matter.
So resist the very human urge to talk about that person and why they are bad.
Because name recognition affects judge elections more than you think. A lot of people are just going to vote for whichever name they've heard most. ๐คท๐ฟโโ๏ธ
Elon is dumping in millions to make sure that as many people have heard that other name as possible.
You can't fight that by also saying that other name.
Talk about this name instead.
Susan Crawford.
That's who they don't want to win.
BINGO!!!
We cannot tolerate what is being done to women, people of color, queer people, and others by the US Federal Government.
like this
GNOME 48 is here, check out what's new:
news.itsfoss.com/gnome-48-releโฆ
GNOME 48 Released With Focus on Your Digital Wellbeing
It took its time, but GNOME 48 is finally here with some rather interesting changes.Sourav Rudra (It's FOSS News)
Tried some of this fancy new "colour film" from Kodak, not sure there's any future in it, but it's a neat trick. They call this one Gold ;)
#BelieveInFilm #KodakGold200 #hasselblad500CM #DogsoOfMastodon
For anyone who saw me experience a frustrating bug in my last stream at @wesley I have found a post about the issue from late last year:
forum.godotengine.org/t/addingโฆ
I donโt have time to write up exactly how this relates to my problem, but iykyk. In the meantime I am trying to come up with a solution.
#GodotEngine #GameDev #GameMath
Adding an instantiated scene to the tree correctly creates a problem?
Well, it solves your problem. Soโฆ Yes! That being said, itโs still quite a bit of extra work to solve a (seemingly) trivial problem. So if I were you, Iโd still open up an issue on GitHub in the hopes of this being avoidable altogether.Godot Forum
This week's comic: Zero dimensional chess
#cartoon #comic #uspol #media #journalism #authoritarianism #democracy
Looking into #ScienceAdvances as a journal to publish in..
Why is there a reference limit, and why is it so low (80 references)? In this day and age? For an online-only journal?
PS: remember that you can rate the submission & revision process of journals on #SciRev scirev.org/
@albertcardona
A handy beginner's tip for switching the default web browser on Ubuntu.
itsfoss.com/ubuntu-change-browโฆ
Change Default Web Browser in Ubuntu [Beginner's Tip]
New to Ubuntu and do not want to stick with Firefox? Here's how you can change your default browser.Sagar Sharma (It's FOSS)
#fediverse #diefraualsmensch #comics
A near perfect satirical essay on the absurdity of working in big tech in 2025.
sfstandard.com/opinion/2025/03โฆ
Build-AGI-faster-so-we-can-fire-you
A modest proposal from the Google co-founder, who believes employees should work 'at least' every weekday. And also every weekend-day.Eli Grober (The San Francisco Standard)
Wine 10.4 continues work on Bluetooth driver and more Vulkan video decoder support in WineD3D gamingonlinux.com/2025/03/wineโฆ
#Wine #Linux #OpenSource
Wine 10.4 continues work on Bluetooth driver and more Vulkan video decoder support in WineD3D
Wine 10.4 is out now as the latest development release of the Windows compatibility layer, bringing new features and assorted bug fixes.Liam Dawe (GamingOnLinux)
#houston .. I mean @Friendica Support and @Friendica Developers, we have a problem!
Look's like bbcode code doesn't get parsed as code on mastodon.
tupambae.org/display/0ac89072-โฆ
troet.cafe/@bitpickup/11420448โฆ
Looks first of all like a troet.cafe specific circunstance @bitpickup, what code is troet running?
The combination of two audio files might be problematic in general. Actually it's not possible over here to upload more than one video or audio and the replay of any of the two files displayed with timer might not work.
What a beautiful story of art and compassion!
The Hidden Heroine of WWI: How Anna Coleman Ladd Restored Faces and Lives
like this
@Ivy Blackledge Whitfield 2025 Oops!
I understand the symbolism behind turning your image black. I have to admit I look for the account with an attached image in order to determine which one is in use. Black is different than a gray outline, but working fast I would have gone with the account with the picture of beautiful ivy greenery.
My apologies.
Iโm the Canadian who was detained by Ice for two weeks. It felt like I had been kidnapped
I was stuck in a freezing cell without explanation despite eventually having lawyers and media attention. Yet, compared with others, I was luckyGuardian staff reporter (The Guardian)
like this
THIS is worth noting:
"Companies like CoreCivic and GEO Group receive government funding based on the number of people they detain, which is why they lobby for stricter immigration policies. Itโs a lucrative business: CoreCivic made over $560m from Ice contracts in a single year. In 2024, GEO Group made more than $763m from Ice contracts.
"The more detainees, the more money they make. It stands to reason that these companies have no incentive to release people quickly. What I had experienced was finally starting to make sense."
like this
like this
FOSS infrastructure is under attack by AI companies thelibre.news/foss-infrastructโฆ Please boost for awareness, reach and to public shame Microsoft, Meta, OpenAI, Perplexity and other such AI companies.
#opensource #programming #Developers
FOSS infrastructure is under attack by AI companies
LLM scrapers are taking down FOSS projects' infrastructure, and it's getting worse.Niccolรฒ Venerandi (LibreNews)
for anyone who was in any of the #GNOME #matrix rooms a week or so ago... the flatpak version of element keeps its cache at ~/.var/app/im.riot.Riot/config/Element/Cache/Cache_Data/. you can use something like wipe to securely erase it.
EDIT: wipe and shred and co. won't work on an SSD. use something like blkdiscard instead.
Is shred bad for erasing SSDs?
Whenever I sold a drive I've zeroed it once with shred from a live environment: sudo shred -vzn 0 /dev/sdX Before I double-checked it wasn't mounted. This is the fastest way to securely erase a dr...Unix & Linux Stack Exchange
@pinguin i didn't see any of the images, but apparently they contained some pretty horrible illegal stuff
if you want a more explicit answer: https://matrix.to/#/!guvcqdhipvyuqxhmyk:gnome.org/$b1prccrdi4979cbes94zqdymylgptbce8utl1w1myn8
Matrix - Decentralised and secure communication
You're invited to talk on Matrix. If you don't already have a client this link will help you pick one, and join the conversation. If you already have one, this link will help you join the conversationmatrix.to
@lorgonumputz @pauldoo alright so according to this: unix.stackexchange.com/a/59334โฆ
shred, wipe, et al just won't work on SSDs because of how they function. the best you can do is a tool called blkdiscard which will politely ask the SSD to wipe the file. failing that, you have to wipe the entire SSD 
Is shred bad for erasing SSDs?
Whenever I sold a drive I've zeroed it once with shred from a live environment: sudo shred -vzn 0 /dev/sdX Before I double-checked it wasn't mounted. This is the fastest way to securely erase a dr...Unix & Linux Stack Exchange
๐ Nextcloud Assistant 3.0: AI Agency in action!
From scheduling meetings to summarizing emails, the Nextcloud Assistant acts on your behalf across Nextcloud apps. Fully self-hosted, modular, and optionalโyour data, your control.
my control, my request that you remove AI from my machine.
The more you fuck around, the harder you will find out.
Get a whole lot of EARTH DEFENSE FORCE in this Humble Bundle gamingonlinux.com/2025/03/get-โฆ
#EARTHDEFENSEFORCE #Gaming #PCGaming
Get a whole lot of EARTH DEFENSE FORCE in this Humble Bundle
On top of the recently launched Humble Heroines Bundle, we also have the just launched EARTH DEFENSE FORCE Collection.Liam Dawe (GamingOnLinux)
The Humble Heroines Bundle returns with some great games for Women's History Month gamingonlinux.com/2025/03/the-โฆ
#SteamDeck #LinuxGaming #PCGaming #Gaming
The Humble Heroines Bundle returns with some great games for Women's History Month
Another chance to pick up some quality games! The Humble Heroines Bundle returns with a different set of great games for Women's History Month supporting Girls Who Code and Girls Make Games Scholarship Fund.Liam Dawe (GamingOnLinux)
noooo why "Beyond two Soul" is part of the bundle ?
The hero is played by a trans man
Even if he was like a woman during the time of the game, now it changes :/
@DamiaB I don't know how to explain
The Last of Us Part II Remastered devs aiming for "best possible experience on handheld gaming devices" gamingonlinux.com/2025/03/the-โฆ
#TheLastofUsPartIIRemastered #TheLastofUs #SteamDeck #PCGaming #Linux
The Last of Us Part II Remastered devs aiming for "best possible experience on handheld gaming devices"
Sony have revealed the system requirements and more info for the PC release of The Last of Us Part II Remastered, which is due to arrive on April 3rd. Looks like it might be good news for Steam Deck owners too.Liam Dawe (GamingOnLinux)
Una coaliciรณn de organizaciones de sociedad civil del Sur global denuncia el creciente dominio del autoritarismo polรญtico y corporativo sobre internet (el poder desenfrenado de la "Broligarquรญa")
Foro Global de Justicia Digital.
#DerechosDigitalesColectivos
apc.org/es/pubs/foro-global-deโฆ
Foro Global de Justicia Digital - Comunicado de Johannesburgo: Es el momento de actuar por la justicia digital
El Foro Global de Justicia Digital, una coaliciรณn de organizaciones de sociedad civil del Sur global, incluida APC, denuncia el creciente dominio del autoritarismo polรญtico y corporativo sobre internet.Asociaciรณn para el Progreso de las Comunicaciones
A crap-sack world that feels oddly like our own. I liked the descriptions of the psychology of folks who are slowly seeing their quality of life degrade but are trying to normalize things for their mental sanity.
(comment on The sheep look up.)
#FabLabFriday #fablab #makers #India #Bengaluru #photography
System Shock 2: 25th Anniversary Remaster arrives June 26 gamingonlinux.com/2025/03/systโฆ
#SystemShock2 #SystemShock #Gaming #PCGaming
System Shock 2: 25th Anniversary Remaster arrives June 26
Nightdive Studios have finally revealed that their System Shock 2: 25th Anniversary Remaster arrives June 26th with a new trailer and new details.Liam Dawe (GamingOnLinux)
Get ready to defend a walking castle in the roguelike action game Castlebound gamingonlinux.com/2025/03/get-โฆ
#Castlebound #IndieGames #Linux #SteamDeck #PCGaming
Get ready to defend a walking castle in the roguelike action game Castlebound
From Ogre Pixel who made Lonesome Village and A Tiny Sticker Tale, their next game is an action roguelike where you're defending a walking castle. Castlebound seems like it could be a lot of fun.Liam Dawe (GamingOnLinux)
The Entertainment Software Association have launched the Accessible Games Initiative gamingonlinux.com/2025/03/the-โฆ
The Entertainment Software Association have launched the Accessible Games Initiative
The Accessible Games Initiative from the Entertainment Software Association (ESA) has been launched, with an aim to improve how developers and stores list clear information about the accessibility features available in video games.Liam Dawe (GamingOnLinux)
Silent Hill 4, F.E.A.R. and more join the GOG Preservation Program gamingonlinux.com/2025/03/sileโฆ
Silent Hill 4, F.E.A.R. and more join the GOG Preservation Program
GOG have just announced another expansion of the the GOG Preservation Program. This is their promise to keep classics updated and working on modern systems.Liam Dawe (GamingOnLinux)
Proton Experimental adds fixes for GTA V Enhanced and more for Linux / Steam Deck gamingonlinux.com/2025/03/protโฆ
#Proton #Linux #SteamOS #SteamDeck
Proton Experimental adds fixes for GTA V Enhanced and more for Linux / Steam Deck
Valve released another smaller update for Proton Experimental, the constantly changing compatibility layer to run Windows games on Linux platforms like the Steam Deck with SteamOS.Liam Dawe (GamingOnLinux)
Everything to grab from Prime Gaming, March 21st edition for Steam Deck / Linux gamingonlinux.com/2025/03/everโฆ
#SteamDeck #Linux #LinuxGaming #PrimeGaming
Everything to grab from Prime Gaming, March 21st edition for Steam Deck / Linux
Here's the up to date list of games available on Amazon Prime Gaming for March 21st, and what compatibility you can expect for Linux / SteamOS and Steam Deck. An easy way to build up your gaming collection.Liam Dawe (GamingOnLinux)
SteamOS 3.7.2 Preview gets a fix for the Steam Deck OLED gamingonlinux.com/2025/03/steaโฆ
SteamOS 3.7.2 Preview gets a fix for the Steam Deck OLED
While Valve continue working towards the public SteamOS 3 release for more devices, and we've seen them note work towards that in the initial SteamOS 3.7 Preview, they continue rolling out more bug fixes for the Steam Deck.Liam Dawe (GamingOnLinux)
Eugen Rochko
in reply to Tristan Colgate-McFarlane • • •