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Items tagged with: microbiology
A patchwork pathway of apparently recent origin enables degradation of the synthetic buffer compound TRIS in bacteria
The widely used synthetic chemical 2-amino-2-hydroxymethyl-propane-1,3-diol (TRIS) was long considered to be biologically inert. Herein, we describe a complete degradation pathway for the catabolism of TRIS in bacteria.bioRxiv
A genome catalogue of lake bacterial diversity and its drivers at continental scale
https://www.nature.com/articles/s41564-023-01435-6
#metagenomics #lakes #freshwater #microbiology
A genome catalogue of lake bacterial diversity and its drivers at continental scale - Nature Microbiology
A metagenomic compendium from lakes across Canada reveals bacterial metabolic potential and how it varies depending on land use in different regions.Nature
Hi again #Mastodon!
I joined the fediverse when a lot of my community had not migrated from the bird site, so could only partially reconstruct it here using automated tools. If I followed you there and don’t here, say hi and let’s reconnect!
For those who don’t know me, I am a #virologist by training with almost 20 years of experience as a #science #editor, a passion for #microbiology and all science really, #OpenScience #openaccess & people
Have a lovely day everyone
Evaluating the role of bacterial diversity in supporting soil ecosystem functions under anthropogenic stress
https://www.nature.com/articles/s43705-023-00273-1
Evaluating the role of bacterial diversity in supporting soil ecosystem functions under anthropogenic stress - ISME Communications
ISME Communications - Evaluating the role of bacterial diversity in supporting soil ecosystem functions under anthropogenic stressNature
Interesting: *Vaginal Microbiota Transplantation (VMT)*
We're probably going to start seeing a lot more of this as we appreciate how microbiomes of different organs impact health and disease.
Personally the key is to have clinical measures of success, as here, not just measuring % of different species changing.
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #microbiome #transplant
Hello everyone!
I’m an associate prof at Virginia Tech studying viral diversity. Lately my group has been focusing on giant viruses, but we are also interested in other protist viruses, and the role of viral endogenization in host genome evolution.
#GiantViruses #ViralDiversity #TreeOfLife #Protists #Microbiology #Bioinformatics #Evolution #Virology #Genomics
Recently we have been examining the strange and complex genes encoded in giant virus genomes!
https://doi.org/10.1093/femsre/fuad053
Amazing structural diversity of giant virus-like particles in forest soil
https://www.biorxiv.org/content/10.1101/2023.06.30.546935v1
#viruses #giantViruses #microbiology
Amazing structural diversity of giant virus-like particles in forest soil
Large DNA viruses of the phylum Nucleocytoviricota infect diverse eukaryotic hosts from protists to humans, with profound consequences for aquatic and terrestrial ecosystems.bioRxiv
New preprint on inter-plasmid competition via type IV-A3 CRISPR systems. Something to think about.
https://www.biorxiv.org/content/10.1101/2023.06.23.546257v1
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans
Type IV-A CRISPR-Cas systems are primarily encoded on plasmids and form multi-subunit ribonucleoprotein complexes with unknown biological functions.bioRxiv
Accounting for 16S rRNA copy number prediction uncertainty and its implications in bacterial diversity analyses
https://www.nature.com/articles/s43705-023-00266-0
#microbiology #bioinformatics #microbiome
Accounting for 16S rRNA copy number prediction uncertainty and its implications in bacterial diversity analyses - ISME Communications
ISME Communications - Accounting for 16S rRNA copy number prediction uncertainty and its implications in bacterial diversity analysesNature
High speciation rate of niche specialists in hot springs
https://www.nature.com/articles/s41396-023-01447-4
High speciation rate of niche specialists in hot springs - The ISME Journal
The ISME Journal - High speciation rate of niche specialists in hot springsNature
My first "reviewed preprint" on @eLife !
A Timeline of Bacterial and Archaeal Diversification in the Ocean
https://elifesciences.org/reviewed-preprints/88268
Lots of hard work from former PhD student in my lab Carolina Martinez. Part of a collaboration with @pseudacris
We are enjoying the new process so far and working on revisions to address some of the concerns raised by reviewers.
https://doi.org/10.1038/s43705-023-00259-z
#microbiology #bioinformatics
Distribution and diversity of ‘Tectomicrobia’, a deep-branching uncultivated bacterial lineage harboring rich producers of bioactive metabolites - ISME Communications
ISME Communications - Distribution and diversity of ‘Tectomicrobia’, a deep-branching uncultivated bacterial lineage harboring rich producers of bioactive metabolitesNature
https://plos.io/3M9uUTH
Beyond pathogenesis: Detecting the full spectrum of ecological interactions in the virosphere
Viral interactions with their hosts are complex and can be beneficial, yet the public perception of viruses is generally negative.plos.io
Mycorrhizae and Land Plants – An Update
by Roberto
I am fortunate that among the first impressions of my day, I take in this view of land plants. Given my proclivity for microbiology my mind inevitably wonders to what I cannot see, the underground network of filamentous fungi connecting the roots of those plants, the mycorrhizae.
Read more → https://schaechter.asmblog.org/schaechter/2023/05/mycorrhiza-and-land-plants-an-update.html
Happy to see the first experimental project I led finally out in the world! With Jeremy Moore, Sydney Olsen, and Mike Travisano
We combined experimental evolution and mathematical modeling to ask: do bacteria evolve to swim away from phages?
1/n
https://doi.org/10.1101/2023.04.29.538831
#microbiology #evolution #ecology #phages #phage #bacteria #MicrobialEvolution #MicrobialEcology
Fight not flight: parasites drive the bacterial evolution of resistance, not avoidance
In the face of ubiquitous threats from parasites, hosts often evolve strategies to resist infection or to altogether avoid contact with parasites. At the microbial scale, bacteria frequently encounter viral parasites, bacteriophages.bioRxiv
Chitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle
As they all needed egg yolks, back at home I'm now making meringues! Lots and lots of meringues!!!
I have no idea how the students mud jars will end up, but here's a pic of one of my winter experiments a couple of years ago with soil/water from the same river...
#WinogradskyColumn #soil #microbiology #StemAmbassador
"To reflect the importance of microbes and to create a home for microbiology research using genetics, PLOS Genetics will be launching a new section on Microbial Genetics. "
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010695
#microbiology #microbes #bacteria #protists #archaea
"the abrupt community changes observed through the time-series could be described as shifts between “alternative stable states“ or dynamics around complex attractors."
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-023-01474-5
#microbiome #microbiology
Alternative stable states, nonlinear behavior, and predictability of microbiome dynamics - Microbiome
Background Microbiome dynamics are both crucial indicators and potential drivers of human health, agricultural output, and industrial bio-applications.BioMed Central
https://www.nature.com/articles/s43705-023-00231-x
#genomics #microbiology
Linking prokaryotic genome size variation to metabolic potential and environment - ISME Communications
ISME Communications - Linking prokaryotic genome size variation to metabolic potential and environmentNature
The methanogen core and pangenome: conservation and variability across biology’s growth temperature extremes
"Increased methanogenic growth temperature is associated with reduced genome size, and thermotolerant organisms...have larger core genome fractions, suggesting that genome size is governed by temperature rather than phylogeny. "
https://academic.oup.com/dnaresearch/article/30/1/dsac048/6862058
#genomics #pangenomics #microbiology
The methanogen core and pangenome: conservation and variability across biology’s growth temperature extremes
Abstract. Temperature is a key variable in biological processes. However, a complete understanding of biological temperature adaptation is lacking, in part becaProndzinsky, Paula (Oxford University Press)
A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias
A large-scale examination of differential RNA expression study datasets submitted to the NCBI GEO repository from 2008-2020 reveals widespread bias, as assessed by the distribution of p values and estimated proportions of true null hypotheses.doi.org
Scaling of Protein Function Across the Tree of Life
"The abundance of functional categories in a given genome scales with genome size, suggesting that universal constraints shape category abundance. Here we look across the tree of life to understand how genome evolution may be related to functional scaling. "
https://www.biorxiv.org/content/10.1101/2023.03.08.531481v1.abstract
#genomics #microbiology
Scaling of Protein Function Across the Tree of Life
Scaling laws are a powerful way to compare genomes because they put all organisms onto a single curve and reveal non-trivial generalities as genomes change in size.bioRxiv
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-023-01467-4
#microbiome #microbiology
Bacterial aerobic methane cycling by the marine sponge-associated microbiome - Microbiome
Background Methanotrophy by the sponge-hosted microbiome has been mainly reported in the ecological context of deep-sea hydrocarbon seep niches where methane is either produced geothermically or via anaerobic methanogenic archaea inhabiting the sulfa…BioMed Central
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad130/7070963?login=false
#plasmids #microbiology
The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG
Abstract. Cells are continuously facing the risk of taking up foreign DNA that can compromise genomic integrity. Therefore, bacteria are in a constant arms raceWeiß, Manuela (Oxford University Press)
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad123/7068371?rss=1
#phages #viruses #microbiology
Identification and characterization of thousands of bacteriophage satellites across bacteria
Abstract. Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit phages for transfer between bacteria. Satellites can encodde Sousa, Jorge A Moura (Oxford University Press)
Fantastic postdoc opportunity in the field of #marine #microbiology @BarIlanU - check out http://www.kranzlerlab.com
Marine Microbial Ecology and Biogeochemistry | Kranzler Lab at BIU | Ramat Gan
Marine microbial ecology and biogeochemistry at the Kranzler Lab at Bar Ilan University.Kranzler Lab at BIU
#evolution #science #microbiology #experiments #time #TimeTravel
High-resolution metagenomic reconstruction of the freshwater spring bloom - Microbiome
Background The phytoplankton spring bloom in freshwater habitats is a complex, recurring, and dynamic ecological spectacle that unfolds at multiple biological scales.BioMed Central
This new research in Scientific Reports takes a #metagenomics and Q-PCR approach to explore the composition of the Cyanobacterial populations and their cyanotoxin production gene in major rivers across the United States (in 2019) and identifies Microcystis as the key toxin producing genus across this study.
Find out more on:
https://www.nature.com/articles/s41598-023-29037-6
#microbiology #ecology #MicrobialEcology
Metagenomic mapping of cyanobacteria and potential cyanotoxin producing taxa in large rivers of the United States - Scientific Reports
Scientific Reports - Metagenomic mapping of cyanobacteria and potential cyanotoxin producing taxa in large rivers of the United StatesNature
#Microbiology #InnateImmunity
https://www.cell.com/cell/fulltext/S0092-8674(22)01584-7
Bacteriophages inhibit and evade cGAS-like immune function in bacteria
Bacteriophages antagonize cGAS-like bacterial immunity by sequestering immune signaling molecules and acquiring capsid gene mutations.Cell
This fascinating new #metagenomics research in mBio explores a potentially important and intriguing link between the presence and relative abundance of different functional guilds present in the human gut #microbiome (including short chain fatty acid biosynthesis and virulence functions) and disease severity and outcomes resulting from the virus. Clearly a subject for future extended studies to explore potential increases in severity due to infection and exacerbated or mitigated by differences in gut microbiomes.
Explore the research on:
https://journals.asm.org/doi/10.1128/mbio.03519-22
#microbiology
This new research in Nature Microbiology explores how hydrogen in seawater supports growth of multiple and diverse #bacterial species.
Fof those (like me) in #Melbourne , you may be interested that the research also includes study of this process within #PortPhillipBay sediments.
Learn more on:
https://www.nature.com/articles/s41564-023-01322-0
#microbiology #bacteria #ecology #MicrobialEcology
Molecular hydrogen in seawater supports growth of diverse marine bacteria - Nature Microbiology
Genome-resolved metagenomics, biogeochemistry, modelling and culture-based analysis reveal that marine bacteria consume H2 to support growth.Nature